This project is made possible by generous financial support from FORMAS, ÅForsk and the Wallenberg Wood Science Center.
The Syrén lab works with different projects related to resource efficiency aiming to contribute to a sustainable society by using biotechnology and biocatalysis. In order to achieve this goal we use synthetic biology and artificial pathway design as well as polymer technology. One current focus is on unraveling the biological mechanisms that generate multicyclic natural products and to reassemble cascades of such biocatalysts for synthesis of fine chemicals and materials through synthetic biology.
Capitalizing on our approach of retrosynthetic analysis in concert with chemoenzymatic catalysis and polymer chemistry, we have generated two novel bio-inspired polymers with rings incorporated into their backbones. For the first time, we have upgraded the monoterpene α-pinene, abundant in waste streams from the paper- and pulp- industry, into a verbanone-derived lactone and corresponding polyesters. We are currently exploring the potential of our newly generated building blocks and green caprolactone analogues in various applications together with industrial partners.